The Nevada State Athletic Commission notified the fighters on Thursday that they will have random drug testing done, and will have to provide samples within 24-hours.
Carwin and Nelson face off at the Ultimate Fighter 16 finale in December.
The Nevada State Athletic Commission is able to randomly drug test fighters in or out of competition, similar to the testing done prior to UFC 146. The commission tested the heavyweight competitors that appeared at a press conference in Las Vegas in late March.
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