OtherGround Forums Dear cancer: f you. Sincerely: mbns

3/25/19 5:44 PM
5/28/02
Posts: 74717

Targeted protein degraders

 

https://www.nature.com/articles/d41573-019-00043-6

3/30/19 7:31 AM
5/28/02
Posts: 74735

https://www.fiercebiotech.com/biotech/turning-point-therapeutics-eyes-100m-ipo-to-propel-drug-resistant-tumor-med

4/5/19 11:37 AM
5/28/02
Posts: 74763

Using crispr to kick pancreatic cancer’s ass

 

https://m.medicalxpress.com/news/2019-04-genome-wide-analysis-reveals-strategies-pancreatic.html

4/16/19 9:17 AM
5/28/02
Posts: 74795

Adcs- another looking promising

 

https://www.fiercebiotech.com/biotech/astellas-seattle-plan-fda-filing-after-cancer-adc-clears-test

4/18/19 8:01 AM
5/28/02
Posts: 74802

Promising new target for pancreatic cancer

https://www.sciencedaily.com/releases/2019/04/190417132744.htm

4/18/19 8:10 AM
1/5/11
Posts: 17707

My wife progressed a bit. Starting kadycyla.

4/18/19 8:14 AM
5/28/02
Posts: 74803

First patient receives stem cell cancer treatment

https://www.10news.com/news/local-news/san-diegan-is-first-patient-to-undergo-novel-cancer-treatment-in-uc-san-diego-clinical-trial

4/18/19 8:15 AM
5/28/02
Posts: 74804
choadler -

My wife progressed a bit. Starting kadycyla.

Adc’s bruh, the ultimate cancer assassin!!

not to derail, but how about that bruins game last night?!?!! 

4/18/19 8:16 AM
9/19/04
Posts: 14985

Anything on non hodgkins peripheral t-cell lymphoma?

4/19/19 11:19 AM
5/28/02
Posts: 74805

Another bladder cancer drug enters clinical trials

https://www.businesswire.com/news/home/20190418005162/en/Vaxiion-Therapeutics-Initiates-Phase-1-Clinical-Trial

4/19/19 11:24 AM
5/28/02
Posts: 74806
STD Machine -

Anything on non hodgkins peripheral t-cell lymphoma?

Yeah, a “few” clinical trials

http://www.tcllfoundation.org/current-clinical-trials

4/23/19 10:35 AM
5/28/02
Posts: 74812

Personalized treatment sends aggressive breast cancer to destination fucked

 

https://www.sandiegouniontribune.com/business/biotech/story/2019-04-22/lethal-cancer-disappears

https://clinicaltrials.gov/ct2/show/NCT02534675

 

4/23/19 10:56 AM
9/19/04
Posts: 15009
microbiologynerd -
STD Machine -

Anything on non hodgkins peripheral t-cell lymphoma?

Yeah, a “few” clinical trials

http://www.tcllfoundation.org/current-clinical-trials

Thank you

4/23/19 8:04 PM
1/5/11
Posts: 17733
microbiologynerd -
choadler -

My wife progressed a bit. Starting kadycyla.

Adc’s bruh, the ultimate cancer assassin!!

not to derail, but how about that bruins game last night?!?!! 

Just read this now, but how bout TONIGHTS game.

 

Nordstrom stepping up. I dunno, I do think Toronto looked better this series. Bruins seem like treading water, but looks like they will likely survive this round.

4/23/19 8:09 PM
12/27/08
Posts: 26618

Muthafuckin SCIENCE

4/23/19 11:50 PM
5/28/02
Posts: 74813

High intensity genomic sequencing and intense dataset analysis will detect cancer at the earliest stages, before symptoms present, all via blood test, allowing docs to fuck cancer before it starts mouthing off

https://grail.com/

 

4/23/19 11:50 PM
5/28/02
Posts: 74814
choadler -
microbiologynerd -
choadler -

My wife progressed a bit. Starting kadycyla.

Adc’s bruh, the ultimate cancer assassin!!

not to derail, but how about that bruins game last night?!?!! 

Just read this now, but how bout TONIGHTS game.

 

Nordstrom stepping up. I dunno, I do think Toronto looked better this series. Bruins seem like treading water, but looks like they will likely survive this round.

Only saw score updates from phone. Twins had their first ever hockey practice :)

7/12/19 8:07 AM
5/28/02
Posts: 75266

ttt

7/12/19 8:11 AM
5/28/02
Posts: 75268

No plasma membrane = no tumor cell survival

https://ucsdnews.ucsd.edu/pressrelease/uc-san-diego-cancer-scientists-identify-new-drug-target-for-multiple-tumor-types

7/25/19 9:50 AM
5/28/02
Posts: 75367

MIT AI tool can predict breast cancer 5 years early. Anything for teh bewbies!!

https://www.google.com/amp/s/techcrunch.com/2019/06/26/mit-ai-tool-can-predict-breast-cancer-up-to-5-years-early-works-equally-well-for-white-and-black-patients/amp/

8/20/19 8:20 AM
5/28/02
Posts: 75587

Myleofibrosis- go fuck yourself

 

https://www.sandiegouniontribune.com/business/biotech/story/2019-08-19/cancer-drug-fedratinib-approved

8/20/19 8:49 AM
8/1/13
Posts: 19173

https://komonews.com/news/nation-world/university-of-findlay-researchers-discover-new-drug-to-treat-brain-cancer

University of Findlay researchers discover new drug to treat brain cancer

INDLAY, Ohio (WNWO) — Statistics show that nearly 40% of all Americans will be diagnosed with cancer at some point during their lifetimes.

But pharmacy students at the University of Findlay are working on a new groundbreaking treatment for one of the deadliest forms.

UF researchers believe they have created a drug to improve that statistic.

"Looking at activity we've seen from drug compounds treating glioblastoma in the past, we've kind of used a molecule called chalcone, that's just a type of drug molecule, but it's something actually found in curry I guess, the food curry," said Reyes.

That's right, the compound called chalcone is most commonly found in curry, the popular Indian food.

Dr. Rahul Khupse is a medicinal chemist working on the project at UF. He grew up in India and said that he discovered chalcone has anti-inflammatory properties as well as anti-cancer properties.

"In my grad school I had worked on natural products and that was kind of like an inspiration for making this designer drug," Dr. Khupse explained.

So his team worked to develop a new compound that they've nicknamed "RK-15."

One of the major breakthroughs about this compound is its selectivity to target only the brain cancer cells while sparing the healthy cells.

"Selectivity is the holy grail of cancer therapy because we know that chemotherapy has a lot of side effects. So how do we achieve that selectivity where our compounds can only kill brain cancer, glioblastoma, and spare the normal brain?" said Dr. Khupse.

Dr. Khupse said that "RK-15" also penetrates the brain-blood barrier, or BBB, which is the brain's defense system, while also targeting the resistant cancer cells.

The team of researchers said this makes "RK-15" 100 times more selective towards the infectious cancer cells.

"What if, by chance, something were to have activity and down the road someday, I look back and think like wow, that's the drug I worked on and here it is saving lives," exclaimed Reyes.

Researchers said the next step is to test on animals, then continue clinical testing on humans before it could get approved by the FDA.

They said it typically takes 10 to 15 years for a new drug to get from the lab to the patient. The team at the University of Findlay is on year two.

8/22/19 8:49 AM
5/28/02
Posts: 75602

https://ucsdnews.ucsd.edu/pressrelease/uc-san-diego-researchers-convert-pro-tumor-macrophages-into-cancer-killers

8/23/19 6:29 PM
5/28/02
Posts: 75619

Dropkick murphys continue to kick ass

 

https://www.wcvb.com/article/mighty-quinn-gets-visit-private-show-from-dropkick-murphys/28799022

8/23/19 8:02 PM
1/14/07
Posts: 10385

I'm walking talking proof that we're getting closer to a cure.