OtherGround Forums Dear cancer: f you. Sincerely: mbns

8/24/19 8:52 AM
6/22/03
Posts: 6488

Hey MBN and Briscoe... since you're in the same spot here:

I have a friend who just got diagnosed with stage 4 colon cancer. She just had surgery and will be starting chemo soon. My understanding from google is that the 5-year survival rate for stage 4 colon cancer is only 15% and it is usually incurable. But Briscoe's fight says the tide might be changing.

What do you recommend for her? Obviously, listening to her oncologist is #1, but are there any super promising next-generation immunotherapies that she should be aspiring to?

8/24/19 9:19 AM
5/28/02
Posts: 75622

Keytruda or opdivo are both immune checkpoint inhibitors that may help. Cancer cells present proteins on their surface that trick the body to recognizing them as normal/healthy cells. Keytruda and opdivo work by identifying the lying cocksucker cancer cells so the body identifies them as foreign and attacks them

8/24/19 9:48 AM
8/15/07
Posts: 16878

ttt

9/4/19 8:10 AM
5/28/02
Posts: 75702

The fak gene can go fak itself

https://ucsdnews.ucsd.edu/pressrelease/fak-protein-linked-to-chemotherapy-resistance-in-ovarian-cancer

9/4/19 8:20 AM
1/5/11
Posts: 18627

Think I just downvoted you mbn. Fucking app + my fat sausage fingers. I'll up vote a few times to even it off!

9/6/19 11:09 AM
5/28/02
Posts: 75712
choadler -

Think I just downvoted you mbn. Fucking app + my fat sausage fingers. I'll up vote a few times to even it off!

Send moar cock pics

9/6/19 11:09 AM
5/28/02
Posts: 75713

Also- new lung cancer targets

https://www.jci.org/articles/view/128654

9/7/19 8:30 AM
5/28/02
Posts: 75735

bacterial kamikaze and rock/paper/scissors to attach tumors

https://www.sandiegouniontribune.com/business/biotech/story/2019-09-05/rock-paper-scissors-cancer

9/9/19 8:00 AM
5/28/02
Posts: 75745

https://www.mlb.com/news/mlb-childhood-cancer-awareness-day

9/13/19 11:40 AM
5/28/02
Posts: 75758

Watch out remicade and all the biosimilars hitting the market, inmunebio's new patent may be better

translation: inmunebio is f'ing cancer in the a

https://www.globenewswire.com/news-release/2019/09/12/1914771/0/en/INmune-Bio-Inc-Announces-USPTO-Allowance-of-Key-Patent-Covering-Its-DN-TNFa-Platform-Technology-for-Treating-Cancer.html

 

9/26/19 12:03 PM
5/28/02
Posts: 75800

Raising $ for local shortys

 

http://give.rchsd.org/site/TR/DIY/LighttheWay?px=1026525&pg=personal&fr_id=1190

10/22/19 8:21 AM
5/28/02
Posts: 75952

Not cancer, but vertex received fast track approval yesterday for a triple combo cystic fibrosis drug that impacts 90% of cf patients

https://www.google.com/amp/s/www.bostonglobe.com/metro/2019/10/21/vertex-wins-fast-approval-for-cystic-fibrosis-drug/hYkfjUoaOcZBYgM45wi9EI/story.html%3foutputType=amp

10/25/19 9:16 AM
5/28/02
Posts: 75976

Personalized breast cancer treatment

 

https://www.sbpdiscovery.org/news/beaker-blog/on-path-to-personalized-breast-cancer-treatments

10/25/19 11:44 AM
1/5/11
Posts: 19017
microbiologynerd -

Personalized breast cancer treatment

 

https://www.sbpdiscovery.org/news/beaker-blog/on-path-to-personalized-breast-cancer-treatments

You are always on the hunt! Going to read it now. Still stable here at home.

 

MBN - remember I reached out about my kid? He's leaning to get his pre-med done during his biomed Bachelor period. It's all working out for him, he's looking for research over summer. He will either work in our ER helping out (EMT type role) or we might get him into one of the research labs. Right now, he wants that MD, but could change obviously.

10/26/19 9:49 AM
5/28/02
Posts: 75977
timeball - I have had rewings, doc martens, Carolinas, ect ect. I just recently bought a pair of timberlands with the composite toe/ metatarsal. They are super light. They feel like dam running shoes. They also have the anti fatigue soles. Only had them for a month, so they haven't had a durability test yet. I like em Phone Post 3.0
I agree about them feeling like tennis shoes. Very comfortable, however the soles and waterproofing only last me 6 months at my job whereas the Redwings last a year. Phone Post 3.0
10/28/19 10:25 AM
8/1/13
Posts: 21300

Huge change in Melanoma prognosis

https://www.medscape.com/viewarticle/920362?src=soc_tw_share

10/28/19 10:54 AM
5/28/02
Posts: 75988

Zejula for wider ovarian cancer indications

https://www.reuters.com/article/us-gsk-zejula-fda/gsk-gets-fda-nod-for-wider-use-of-ovarian-cancer-drug-zejula-idUSKBN1X22V5

11/3/19 7:52 PM
5/28/02
Posts: 76020


mrs mbns company raised $14k saturday night for the leukemia and lymphoma society's "light the night" campaign. always giving back- in the lab and with $$
11/7/19 10:24 AM
5/28/02
Posts: 76027

Major CAR-T player Tmunity getting major fucking funding. Keeping an eye on this, as they have a legit shot at royally fucking cancer in the ass

 

https://www.fiercebiotech.com/biotech/andreessen-horowitz-leads-75m-round-for-tmunity-as-it-eyes-phase-2-studies-for-2021

11/18/19 11:10 PM
5/28/02
Posts: 76083

https://www.nbcconnecticut.com/news/sports/CCSU-Football-Player-Meets-His-Bone-Marrow-Match-564712232.html

11/19/19 4:12 PM
1/5/11
Posts: 19253

MBN is a good shit. He knows I follow this thread quite a bit. VU for lifetime for MBN.

 

Today, crispr tech study results... 2 patients, 1 w beta thalassemia, 1 with sickle cell. They claim the 2 patients are CURED. The beta thalssemia pt needed 16 transfusions last year. Since the one time treatment, he has not needed any transfusion.

 

If real, and it sounds pretty damn good right now. Hope it's true. Just one more step toward wiping some of this shit off the planet.

11/19/19 8:13 PM
2/5/05
Posts: 49044

My buddy had stage 3 or 4 cancer. Diagnosed in feb. 

100% cancer free and thriving in October.

fuck you cancer. You don't get them all!  

11/19/19 9:19 PM
5/28/02
Posts: 76086

https://m.theepochtimes.com/loyal-boyfriend-who-stuck-with-girlfriend-during-breast-cancer-proposes-on-her-last-day-of-chemo_3130408.html

11/20/19 10:48 AM
1/5/11
Posts: 19262
microbiologynerd -

https://m.theepochtimes.com/loyal-boyfriend-who-stuck-with-girlfriend-during-breast-cancer-proposes-on-her-last-day-of-chemo_3130408.html

Good guy there. I almost dumped my wife's ass after diagnosis. She was close to getting the boot, bit then I figured that she can still do laundry and cook despite chemo. I'm gonna let her stick around for a bit, providing my tighty-whiteys are pressed daily.

11/27/19 12:45 PM
5/28/02
Posts: 76110

Damn choadler!

also- more reasons why we do what we do. kids unnastan, kids get it

http://nedhardy.com/2019/06/17/doctor-ask-terminally-ill-kids-what-really-matters-in-life-here-are-their-answers/