prof - For the medical professionals:
One worry has been that if there is a second wave of COVID-19
it could coincide or overlap with the flu season, hence putting far more pressure on the health care system and hospitals than we are even seeing now.
On the other hand, it seems there may be some factors mitigating that scenario:
1. We will in all likelihood still have in place the type of physical distancing practices we've become accustomed to, and other practices, that have "lowered the curve" infection rate for COVID. It would seem other contagious disease infection rates like The Flu would also be much lower due to this as well. (Of course if COVID rates in a second wave are maintained just below hospital capacity, even reduced flu infection could push hospitalizations above the threshold).
2. Hopefully we will be better prepared in a second wave, having ramped up production of PPE and other necessary equipment, having established better emergency care plans for overflow, etc.
So one thing I haven't seen info on yet:
Are infection rates for any other diseases down at this time, due to physical distancing etc - colds, flu, whatever?
When I checked a week or two ago, flu deaths were in line with historical expectations if you adjusted for the lag in reporting that we tend to see.
Comparing non-COVID deaths after the fact will definitely help us suss out the accuracy of our diagnoses in absence of real testing and arguably help us understand which pre-existing conditions get fucked by COVID. Everyone jokes about inflated numbers for pre-existing conditions, but you can have a great prognosis and life expectancy with diabetes but get mouth fucked by COVID.
The research on obesity, diabetes, and smoking as COVID risk factors is still nascent but already pretty damning.
The diabetes tie in could be the fact that now they have started to explore ARBs and ACEi in diabetes.
In patients with type 2 diabetes, hypertension, and microalbuminuria, ACE inhibitors and ARBs have been shown to delay the progression to macroalbuminuria. (A) In those with type 2 diabetes, hypertension, macroalbuminuria (>300 mg/day), and renal insufficiency, an ARB should be strongly considered.
IMO if they want to really tackle this. Target ACE2 and find a workaround for the Mas pathway to alleviate ARDS